The question is from Round $1$ of $1996/97$ Iranian National Mathematical Olympiad. My attempt at a solution is as below:
$a,b,c,d$ cannot all be odd because then their sum would be even and therefore not prime. So, at least one of $a,b,c,d$ is even. Given that $ad=bc$, at least two of $a,b,c,d$ are even. If only two of $a,b,c,d$ are even, then $a+b+c+d$ is even and is not prime. Therefore, the only possibility is that three of $a,b,c,d$ are even.
Without loss of generality, let $a,b,c$ be even. Using $ad=bc$, we can prove that (after cancelling out any higher powers of $2$ that $a,b,c$ might share), $a\equiv 0\pmod 4$, $b\equiv 2\pmod 4$ and $c\equiv 2\pmod 4$, basically that $a$ has one extra power of $2$ than $b,c$.
I am stuck after this and do not know how to proceed
Since $d = bc/a$ is an integer, we can factor $d = (b/x)(c/y)$ for some positive integers $x,y$ such that $b/x$ and $c/y$ are integers and $xy=a$. (This is intuitively clear and can be made rigorous by playing around with prime factorizations of $a,b,c$.)
Then $$ a + b + c + d = xy + b + c + (b/x)(c/y) = (x + c/y)(y + b/x) $$ which is always a nontrivial factorization, so $a+b+c+d$ cannot be prime.