Dirichlet's theorem says that for any two positive coprime integers $a$ and $d$, the arithmetic progression $a,a+d,a+2d,a+3d,\ldots$ contains infinitely many prime numbers. In other word, there are infinitely many prime numbers of the form $a+nd$.
What can be said if $a$ is negative (and $d$ is still positive)?
In particular, if $a=-1$ (for which it seems to be known that the answer is positive, namely, there exist infinitely many prime numbers of the form $-1+nd$).
$a$ and $d$ are still assumed to be coprime, since otherwise there is no chance to obtain primes of the form $a+nd$, because we have: $a+nd= \gcd(a,d)\tilde{a}+n\gcd(a,d)\tilde{d}=\gcd(a,d)(\tilde{a}+n\tilde{d})$; notice that this shows that there are infinitely many primes $P$ such that $a+nd$ equals $\gcd(a,d)P$.
Thank you very much!
Edit: Robin Chapman mentions the case $a=-1$ in this question, but there is no explanation there, only a reference.
If $a$ is negative, you can write $a+nd = (a+kd)+(n-k)d$ where $kd>-a$, which gives an equivalent statement with positive integers. In other words, the sign of $a$ is unimportant. $d$ needs to be positive so that there are infinitely many positive terms in the sequence in the first place.