How can we solve $$y'''(t)+a(y''(t))^2+b(y'(t))^3=0$$
Could one make some kind of least common denominator argument to decide possible substitutions? Since the chain rule will come into play, I suppose a substitution both for the variable $t$ and the function $y$ could be useful. Possibly some powers of them?
As Adrian suggests, let $y'=z$, to get the second order equation $$ z''+a\,(z')^2+b\,z^3=0. $$ Since the independent variable $t$ does not appear explicitly in the equation (I am assuming $a$ and $b$ are constants), we let $$ z'=p,\quad z''=\frac{dp}{dt}=\frac{dp}{dz}\,\frac{dz}{dt}=p\,\frac{dp}{dz}. $$ This gives the first order equation $$ p\,\frac{dp}{dz}+a\,p^2+b\,z^3=0, $$ which written as $$ \frac{dp}{dz}=-a\,p-b\,z^3\,p^{-1} $$ is a Bernoulli equation. To solve it, let $u=p^2$. This gives the linear equation $$ \frac{du}{dz}=-a\,u-b\,z^3. $$ I have not done the calculations, but my impression is that you will not be able to get an explicit solution in terms of elementary functions.