I've seen recently for the first time in Special Functions (by G. Andrews, R. Askey and R. Roy) the definitions of fractional integral
$$(I_{\alpha }f)(x)=\frac{1}{\Gamma (\alpha )}\int_{a}^{x}(x-t)^{\alpha -1}f(t)dt\qquad \text{Re}\alpha >0$$
and fractional derivative
$$\frac{d^{\nu }w^{\mu }}{dw^{\nu }}=\frac{\Gamma (\mu +1)}{\Gamma (\mu -\nu +1)}w^{\mu -\nu },$$
in The Hypergeometric Functions Chapter.
I would like to know some applications for Fractional Calculus and/or which results can only be obtained by it, if any.
Fractional derivatives can be used to establish connections between various special functions. The book An Atlas of Functions makes heavy use of this, especially derivatives of order 1/2 and -1/2.
Also, the existence of fractional derivatives is related to the convergence of Fourier transforms. For example, if a function has a 1/2 a derivative that means you can multiply its Fourier transform by $x^{1/2}$ and it is still in $L^2$. But I haven't seen much use in actually computing fractional derivatives, only knowing that they exist.
On a somewhat related note, see my answer to a question on Math Overflow related to Sobolev spaces.