Given the Collatz function and its iterates: $$ T(n) = \begin{cases} n/2, & \text{if $n$ is even} \\ (3n+1)/2, & \text{if $n$ is odd} \end{cases} $$ and $$ T^{k}(n) = T(T^{k-1}(n)).$$
Question. How does one apply iterates to large integers such as $$ n = \big(3756801695685 \; \times \;2^{666669}\big) – 1\: ?\label{1}\tag{1} $$
We can begin by observing that repeated application of the Collatz function to numbers of the form $$ m = (2^{k} \times p) – 1 $$
where p is an odd integer, results in the iterate:
$$ T^{k}(m) = ((3^{k} \times p) – 1), $$
Thus, the trajectory of m travels k steps to arrive at a step that is $(3/2)^{k}$ times greater than m.
Applying this to the example in \eqref{1} yields a trajectory that spans 666669 consecutive odd numbers to arrive at
$$ T^{666669}(n) = \big(3756801695685 \times 3^{666669}-1\big). \label{2}\tag{2} $$
NOTE:
$$ 3756801695685 = 3 \times 5 \times 43 \times 347 \times 16785299 $$
Rephrasing the question: Are there similar ways to shortcut the evaluation of remaining iterates?
$\forall k, \forall \alpha \in \mathbb{N}:$
So $T^{k+1}(\alpha\,2^{k+1} + 2^k - 1) = \alpha\,3^k + \frac{3^k - 1}{2}\quad\equiv \alpha + k\ (\text{mod } 2)$
After that, I have some relations, but less general.
These formulas can be proved by induction. But with a mixed representation in base 2 and 3, these formulas become obvious. Because
Where $(\dots)_2$ is a binary representation and $(\dots)_3$ a representation in base $3$. Something like $\alpha:(0101)_2:(2)_3$ represents $\alpha \times 2^4 \times 3 + (0101)_2 \times 3 + (2)_3 = \alpha \times 2^4 \times 3 + 5 \times 3 + 2 = \alpha \times 2^4 \times 3 + 17$. And it is possible to mix figures in base 2 and figures in base 3.
(A little online tool to manipulate this kind of mixed radix.)
$\forall k, \forall \alpha \in \mathbb{N}:$
So $T^{k+1}\big(\alpha:(0\underbrace{1\dots11}_{k\text{ times}})_2\big) = \alpha:(\underbrace{1\dots11}_{k\text{ times}})_3\quad\equiv \alpha + k\ (\text{mod } 2)$