Are these lines perpendicular - 3 dimensional parametric equations

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I was given a problem asking to state whether or not two given lines were perpendicular of parallel, and to find the angle between them. These are lines in 3 dimensional space, and are defined by parametric equations. Here is a picture of one of the problems:

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Do I need to test these by checking their dot product and cross product? How do I find that if I have an equation not a vector? (I know I need to include my work - just I've been trying to work this problem and haven't gotten anywhere. I really don't know how to do it. )