Assuming $y_1$ and $y_2$ are two solutions of $y'' +p(x)y' +q(x)y=0$, find a first order constant coefficient DE satisfied by Wronskian, and solve it

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$$y'' +p(x)y' +q(x)y=0$$ Assuming $y_1$ and $y_2$ are two solutions of the given DE, find a first order constant coefficient DE satisfied by their Wronskian, and solve it.

I don't really understand how to approach this. The DE has to be constant-coefficient and first-order but how do I get it from this with just knowing that $y_1$ and $y_2$. I mean what does the second part have to do with the given equation?