Let $P\in\mathbb{R}[x,y]$ be called a bijective polynomial iff these two conditions hold.
- If $a,b\in\mathbb{Z}^+$, $P(a,b)\in\mathbb{Z}^+$.
- For each $x\in\mathbb{Z}^+$, a unique pair of integers $a,b\in\mathbb{Z}^+$ exists such that $P(a,b)=x$.
I then wish to find all bijective polynomials. My conjecture is that the polynomial $$P(x,y)=\frac{1}{2}(x^2+y^2+2xy-x-3y+2)$$ and its transpose are the only ones, and I've tried to prove that no such polynomials exist with degree greater than 2 via some kind of growth argument, but I haven't been able to do so.
Here's a (very crude) visualization of how the bijective polynomial given above works.

This is a century old conjecture. These two polynomials are known as the Cantor pairing polynomials.
Some results are known:
Reference: https://arxiv.org/pdf/1512.08261.pdf