I found this aproximation
$$ \binom{n}{k}\sim \frac{n^k}{k!} $$
But there was a note that said this holds just when $n>>k$, why is this? I need to consider this binomial coefficient when $k$ is near of $n/2$ and I would like use this or any similar expression to avoid some factorials.
You can write the coefficient as $\frac {n(n-1)(n-2)\ldots (n-k+1)}{k!}$ When $n \gg k$ the numbers you subtract from $n$ in the numerator may be too small to matter. If you ignore them you get the approximation $\frac {n^k}{k!}$ When $k$ is near $\frac n2$ this is not a good approximation. Stirling's approximation is quite accurate, leading to the approximation of the central binomial coefficient $${2n \choose n} \approx \frac {4^n}{\sqrt {\pi n}}$$