Calculating higher homotopy groups of (complements of) knots

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There are techniques to calculate the group of a knot, i.e. the fundamental group of its complement in a manifold, but are there techniques to calculate its higher homotopy groups?

Can anyone suggest a reference on this topic?

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MR0090053 (19,761a) Reviewed
Papakyriakopoulos, C. D.
On Dehn's lemma and the asphericity of knots.
Ann. of Math. (2) 66 (1957), 1–26.
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It is proven that knot completements in $S^3$ are aspherical (all higher homotopy groups vanish)