Let $K$ be a field and define a ring morphism $$\psi: K[x_1,x_2, \dots , x_n, y_1, y_2, \dots , y_n] \rightarrow K(x_1,x_2, \dots , x_n)$$ by $\psi(x_i) =x_i$ and $\psi(y_i) =\frac{1}{x_i}$.
I think that $\ker(\psi) = \langle x_iy_i - 1\rangle _ {1 \leq i \leq n}$ but I've not been able to prove it.
The inclusion $\ker(\psi) \supseteq \langle x_iy_i - 1\rangle _ {1 \leq i \leq n}$ is trivial.
For the other inclusion all I could do was to prove that if $p$ is in $\ker(\psi)$ then there exist $p_1, p_2, \dots , p_n \in K(x_1,x_2, \dots , x_n)$ such that $p = (x_1y_1 - 1)p_1 +(x_2y_2 - 1)p_2 +\dots +(x_ny_n - 1)p_n$.
Any idea?
Try arguing by induction on $n$.
Write $\psi_{n}$ rather than $\psi$ (to indicate the dependence on the choice of $n$).
Also, write $\phi$ to denote morphism $$K(x_1,\ldots,x_{n-1}) [x_n,y_n] \to K(x_1,\ldots,x_n)$$ given by $y_n \mapsto x_n^{-1}$; so $\phi$ is an analogue of $\psi_1$ but with the coefficient field $K$ replaced by the larger field $K(x_1,\ldots,x_{n-1})$, and with the variables $x_n,y_n$ being used rather than $x_1,y_1$.
Notice that $\psi_n$ factors as $\psi_n = \phi \circ \psi_{n-1}$.
Now suppose you have proved the base case $n = 1$. Then (taking into the account the preceding remark that $\phi$ is just $\psi_1$, but with a different coefficient field and differently labelled variables) you know the kernel of $\phi$. By induction, you can also assume that you know the kernel of $\psi_{n-1}$. Now by a fairly easy argument using the factorization of $\psi_n$, you can compute the kernel of $\psi_n$.
This reduces you to the case $n = 1$, which is basically covered by user26857's comment above (and is easy to check in any case).