$ 2^{-\sqrt{x}}$ is positive, decreasing, continuous, so we can use the integral test.
$\int \limits_{1}^{\infty} \sqrt{x} \, 2^{-\sqrt{x}} = \lim \limits_{T \to \infty} \int \limits_{1}^{T} \sqrt{x} \, 2^{-\sqrt{x}} dx$.
And now, how to calculate $\int \limits_{1}^{T} \sqrt{x} \, 2^{-\sqrt{x}} dx$?
Substitution $u = \sqrt{x}$ obviously does not work.
With the substitution $u = \sqrt{x}$, we find $$ \int_1^T \sqrt{x}\,2^{-\sqrt{x}}dx = \int_{1}^\sqrt{T} u\,2^{-u} \ 2\sqrt{x}\ du = \int_{1}^\sqrt{T} u\,2^{-u} \ 2u\ du = 2\int_{1}^\sqrt{T} u^2 2^{-u} $$ This integral can be done using integration by parts. We find that the improper integral converges.