The integral is
$$\int^3_1\sqrt{16-x^2}dx$$
I've used the trig substitution method, replacing $x$ with $4\sin\theta$:
$$x=4\sin\theta, \quad \theta=\arcsin\left(\frac x4\right), \quad dx=4\cos\theta \ d\theta$$ (I've excluded the intervals for the definite integral for now) \begin{align} I&=\int\sqrt{16-16\sin^2\theta} \ 4\cos\theta d\theta \\ &=\int\sqrt{16\cos^2\theta}\ 4\cos\theta d\theta\\ &=\int4\cos\theta 4\cos\theta d\theta \\ &=16\int\cos^2\theta d\theta \\ &=16\int\frac{\cos2\theta}{2}d\theta \\ &=8\int \cos2\theta d\theta\\ &=\left[4\sin2\theta\right]^{\arcsin(3/4)}_{\arcsin(1/4)}\\ &=4\sin\left(2\arcsin\frac 34\right)-4\sin\left(2\arcsin\frac 14\right)\\ \end{align} At this last step, I'm not sure how to simplify the 2 arcsin part. It doesn't simplify because of the 2 in front of the arcsin, is there any other way? Or did I just do the wrong method to solve this integral in the first place?
First of all your double angle integral $$16\int(\frac{cos2\theta}{2})d\theta$$
should have been
$$ 16\int\frac {1}{2}(1+cos2\theta) d\theta$$
Towards the end of your solution, you asked for $$\sin(2 arcsin(1/4)).$$
Use double angle formula $$\sin(2x)=2 \sin(x) \cos(x)$$ and use the fact that $$\sin x =1/4.$$