Let p=(px,py),q=(qx,qy), and r=(rx,ry).Show that the sign of the determinant
|1 px py|
D=|1 qx qy|
|1 rx ry|
determines whether a point r lies to the left or right of the directed line pq. ( I know that this true, not exactly sure how to show this)
We know that we can write the line $PQ$ as
$$k_1x+k_2y=1$$
And we know it is satisfied for both point $P$ and point $Q$. So we have a system of equations:
$$\begin{cases} k_1p_x+k_2p_y=1\\ k_1q_x+k_2q_y=1 \end{cases}$$
We can solve for both $k_1$ and $k_2$ because this is two equations and two unknowns.
$$k_1 = \frac{p_y-q_y}{p_yq_x-p_xq_y}$$ $$k_2 = \frac{q_x-p_x}{p_yq_x-p_xq_y}$$
Which just means we can rewrite our equations as:
$$(p_y-q_y)x+(q_x-p_x)y=p_yq_x-p_xq_y\tag{1}$$
Consider the matrix $A$
$$A=\left[\begin{matrix}1 & p_x & p_y\\ 1 & q_x & q_y\\ 1 & r_x & r_y\end{matrix}\right]$$
You can work out that $\det[A]=(p_xq_y-p_yq_x)+(p_yr_x-p_xr_y)+(q_xr_y-q_yr_x)$
Clearly, if $R$ is on the line, then $x=r_x$ and $y=r_y$ satisfies $(1)$ and we have
$$(p_yr_x-p_xr_y)+(q_xr_y-q_yr_x)=p_yq_x-p_xq_y$$
which is the same as
$$(p_yr_x-p_xr_y)+(q_xr_y-q_yr_x)+(p_xq_y-p_yq_x)=0=\det[A]$$
So if $\det[A]=0$, then the point $R$ is on the line $PQ$.
Now suppose that $\det[A]\ne0$ which means that $R$ is not on the line. Let $r_y'$ be such that the point $R'=(r_x,r_y')$ is on the line.
We can solve for $r_y'$ in $(1)$
$$r_y'=\frac{p_yq_x-p_xq_y+r_x(q_y-p_y)}{q_x-p_x}$$
If $\det[A]>0$ then $(p_yr_x-p_xr_y)+(q_xr_y-q_yr_x)+(p_xq_y-p_yq_x)>0$. We can isolate $r_y$ in this inequality and get
$$r_y>\frac{p_yq_x-p_xq_y+r_x(q_y-p_y)}{q_x-p_x}=r_y'$$
Therefore, if $\det[A]>0$ then $r_y>r_y'$. And since we know that $R$ and $R'$ share an $x$ value, we know that $r_y$ is above $r_y'$ which is on the line. And therefore we know that $r_y$ is above the line.
The exact same is followed for $\det[A]<0$ to show $r_y$ is below the line. It would be redundant to type it all out.
I'm sure there is a much more elegant solution using the fact that we are using a right hand coordinate system and we are essentially checking the direction of the cross-product of a particular pair of vectors that relates to the question. But this is a very fundamental way to show that it works.