In the example in the following slide, we follow the highlighted formula. With regard to the highlight, I'm confused why the number is greater or equal to $2^{n-1}$, while only need to be less than $2^n$ (not less than or equal to $2^n$)?

determining the number of bits required to represent a number in binary
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What the example is illustrating is a general rule: if you have a positive whole number $x$ that you want to write in binary, and if
$$ 2^{n-1} \leq x < 2^n $$
where $n$ is a whole number, you need exactly $n$ bits to write $x.$
I hope you will agree that since the number $48$ is not a power of two, it really does not matter (for a number like that) whether we write $\leq$ or $<.$
But what if we want to write $64$ in binary? If the rule were
$$ 2^{n-1} \leq x \leq 2^n $$
then $64$ (which is equal to $2^6$) would fit the rule in two ways: it would fit with $n=6,$ because $2^(6-1)\leq 64\leq 2^6,$ and it would fit with $n=7,$ because $2^{7-1}\leq 64\leq 2^7.$
But it cannot be true both that it takes exactly $6$ binary bits to write $64$ and that it takes exactly $7.$ So this is not a good rule.
In fact you need $7$ bits to write $64.$ Notice that this is the answer you get if you write $\leq$ for $2^{n-1}$ but $<$ for $2^n.$
Another way to describe the rule with fewer symbols and more words is that you need exactly $n$ binary bits to write $x$ if $x$ is less than $2^n$ but not less than $2^{n-1}.$
Think of a number with $n$ bits. Each bit can be 0 or 1, so you have $2^n$ combinations. However one of the combinations is the number 0 (i.e. all $n$ bits are 0). So you can only count up to $2^n-1$ with $n$ bits and not all the way up to $2^n$. That's why you see $<2^n$ in your example and not $\leq 2^n$.