My Approach:
I'm assuming that $\{1,x,x^2,\dots\}$ is $P(R)$, the set of all polynomials.
Suppose $\{1,x,x^2,\dots\}$ spans $F(R)$. Then by definition $F(R) = \text{span } P(R)$. However, $P(R)$ is a subspace of $F(R)$ and as a result, $P(R)$ can not span $F(R)$.
Sorry in advance if this is not the best proof/approach.
It would be simpler to note that, since each of the functions $1$, $x$, $x^2$, … is continuous, all the functions from the space that they span is continuous too. But there are discontinuous functions in $F(\mathbb{R})$.