If we add any finite number of any distinct prime reciprocals, will the result always be an irreducible fraction?
If not, is there any bound on the value of a greatest common divisor for the numerator and demoninator of such fraction?
This boils down to the question about the greatest common divisor for:
$$Q=p_1p_2 \cdots p_n~~~~\text{and}~~~~P=\sum_{k=1}^{n} \frac{Q}{p_k}$$
Here $\{p_k\}$ is any finite subset of primes.
If this question is trivial, I apologise in advance. I checked this quickly for small primes and got only irreducible fractions. Elementary number theory is not my strong point.
For distinct primes $p_1,\dots,p_n$ the fraction $S=\frac{1}{p_1}+\cdots+\frac{1}{p_n}$ is always irreducible. For if it were reducible, some $p_i$ would "cancel", without loss of generality $p_1$. So we could express $S$ as $\frac{A}{p_2p_3\cdots p_n}$.
Multiply both sides of the equation $$\frac{1}{p_1}+\frac{1}{p_2}+\cdots+\frac{1}{p_n}=\frac{A}{p_2p_3\cdots p_n}$$ by $p_2p_3\cdots p_n$. On the right-hand side we obtain an integer. On the left-hand side we do not.