Supposing that solution exists, I've found that $x$, $y$, $(x+y)$, $(x-y)$ should be pairwise coprime numbers, and hence $x$ and $y$ are coprime of different parity. And after that I can not make any step further.
2026-04-25 15:48:09.1777132089
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Does equation $xy(x+y)(x-y)=10z^2$ have nonzero integer solutions?
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Sort of interesting. I replaced the $10$ with $2730$ in order to get at least one solution, it suddenly gave many:
Thu Dec 7 15:53:49 PST 2017
10 3 2730 = 2 3 5 7 13
13 7 10920 = 2^3 3 5 7 13
13 8 10920 = 2^3 3 5 7 13
14 1 2730 = 2 3 5 7 13
15 13 10920 = 2^3 3 5 7 13
21 5 43680 = 2^5 3 5 7 13
1573 128 494892478080 = 2^7 3^5 5 7 11^2 13 17^2
1694 1681 124939064250 = 2 3^3 5^3 7 11^2 13 41^2
1701 1445 1979569912320 = 2^9 3^5 5 7 11^2 13 17^2
3375 13 499756257000 = 2^3 3^3 5^3 7 11^2 13 41^2
3610 3267 27819510288570 = 2 3^3 5 7^3 11^2 13 19^2 23^2
6877 343 111278041154280 = 2^3 3^3 5 7^3 11^2 13 19^2 23^2
Thu Dec 7 15:55:10 PST 2017
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Multiplier set to $6$
Thu Dec 7 16:47:57 PST 2017
2 1 6 = 2 3
3 1 24 = 2^3 3
25 24 29400 = 2^3 3 5^2 7^2
49 1 117600 = 2^5 3 5^2 7^2
2738 529 10452831898806 = 2 3^3 11^2 23^2 37^2 47^2
3267 2209 41811327595224 = 2^3 3^3 11^2 23^2 37^2 47^2
Thu Dec 7 16:50:07 PST 2017
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Multiplier set to $7,$ and checked for $0<y < x < 11000$
Thu Dec 7 16:56:20 PST 2017
16 9 25200 = 2^4 3^2 5^2 7
25 7 100800 = 2^6 3^2 5^2 7
Thu Dec 7 16:58:08 PST 2017
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Multiplier set to $14$
Thu Dec 7 17:15:36 PST 2017
8 1 504 = 2^3 3^2 7
9 7 2016 = 2^5 3^2 7
4225 2016 117426776594400 = 2^5 3^2 5^2 7 13^2 47^2 79^2
6241 2209 469707106377600 = 2^7 3^2 5^2 7 13^2 47^2 79^2
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The original question is equivalent to asking whether $10$ is a congruent number - which it isn't.
With a general multiplier $N$, we have \begin{equation*} xy(x+y)(x-y)=Nz^2 \end{equation*}
Define $t=x/y$ and $w=z/y^2$ giving \begin{equation*} t(t+1)(t-1)=Nw^2 \end{equation*} and then define $s=Nt$ and $r=N^2w$ leading to \begin{equation*} r^2=s^3-N^2s \end{equation*} which is the elliptic curve for the congruent number problem.
Non-zero solutions only come from curves with rank greater than zero. This includes $N=5,6,7$ which give curves of rank $1$. $N=2730$ gives a curve of rank $2$ using Denis Simon's ellrank code.