It's well-known (assuming the axiom of choice) that the inclusion $\ell^1 \subset (\ell^1)^{**}$ is proper as a simple corollary of the Hahn-Banach theorem. But is this the end of the dualizing process; e.g., does $(\ell^1)^{**} = (\ell^1)^{****}$, or do we continue to get more unwieldy vector spaces over time? If this process does not terminate, is there a non-trivial (i.e. not 'reflexive') condition on vector spaces $V$ such that, for some large enough $n$, $V^{2n*}=V^{(2n+2)*}$?
On a similar topic, if we deny the axiom of choice, we know that $(\ell^1)^{**}=\ell^1$ (source). In this case, do we also have $V^{**}=V$ for all $V$?
Interestingly, there are exactly two possibilities: a Banach space is either reflexive or its chain of double duals never terminates. This only uses a couple of facts: $(1)$ a Banach space is closed in its dual and $(2)$ a closed subspace of a reflexive vector space is reflexive. $(1)$ is a fact about any complete subspace of a metric space.
Here's $(2)$, suppose $X\subset B$ is closed and $B=B^{**}$. Then any element $\xi$ of $X^{**}$ corresponds to an element $\xi_B$ of $B^{**}$ acting on $L\in B^*$ by restriction, $\xi_B(L)=\xi(L|_X)$. On the other hand since $B$ is reflexive $\xi$ corresponds uniquely to $x\in B$, that is, $\xi_B(L)=\xi(L|_X)=L(x)$. This shows that if $L$ vanishes on $X$, $L(x)=0,$ so since $X$ is closed $x\in X$.
So, suppose $X$ is a Banach spaces and its chain of double duals eventually stabilizes, say the $n$th double dual is isomorphic to the $n+1$st. Then the $n$th double dual is reflexive, and being a closed subspace, so is $X$ itself.
I was going to avoid commenting on the set theoretic part of your question, since I don't know much about alternatives to the axiom of choice. But having just checked your link the answer, which is no, is actually there: in Zermelo-Frankel set theory with dependent choice and the axiom that all sets of real numbers have the property of Baire, the double dual of $(\ell^\infty/c_0)^{**}=0$. But it certainly doesn't require the axiom of choice to show there are bounded sequences that don't converge to zero! So $\ell^\infty/c_0\neq 0$ even in that system, and in the absence of choice a Banach space needn't even embed into its double dual.