Assuming $0^0=1$, how to prove/disprove the existence of integers $n,s$ such that $0\le s\le n\ge 1$ and $$\left({2\,s\over n}\right)^s\left({2\,(n-s)\over n}\right)^{n-s}\in\left\{{1\over 9},\,9\right\}$$ ... or, equivalently, satisfying either one of the following two equations: $$\begin{align}&\quad 2^n\,s^s\,(n-s)^{n-s}=9\cdot n^n\tag{1}\\ &\quad 9\cdot2^n\,s^s\,(n-s)^{n-s}=n^n\tag{2} \end{align}$$ Clearly there can be no solution with odd $n$, as in that case both (1) and (2) have odd RHS and even LHS; but other than that, I don't see how to proceed. Brute force searching turns up no solutions, and of course the numbers quickly become infeasible to compute. It appears that for both (1) and (2), $\min_{0\le s\le n}$|LHS-RHS| diverges as $n\to\infty$, but how to prove that? (Apologies if there's something obvious that I'm just not seeing.)
An equivalent of this question arose while answering another (in the proof sketched for Question #1 there): Discontinuities in the expectation of a stopping time (Bayesian coin-tossing) .)
To show that there are no solutions, it suffices to show that both $n$ and $s$ are multiples of $3$, as then the factors $2^n$, $s^s$, $n^n$ and $(n-s)^{n-s}$ are all perfect cubes. The remaining factor $9$ is not a perfect cube, a contradiction.
First, if $s=0$ or $n=0$ or $n-s=0$ then, dividing out common factors, the equations simplify to $$2^n=9\qquad\text{ and }\qquad 9\cdot2^n=1,$$ which are clearly impossible, and therefore $n>s>0$.
Now starting off with the second equation, if $$9\cdot2^n\cdot s^s(n-s)^{n-s}=n^n,$$ then it is clear that $3$ divides $n$, so $n=3m$ for some positive integer $m$. It follows that the right hand side is divisible by $3^3$, and hence $s$ is divisible by $3$, and we are done.
The other case is similar; if $$2^n\cdot s^s(n-s)^{n-s}=9n^n,$$ it is clear that $3$ divides either $s$ or $n-s$, or both. In any case, because $s,n-s>0$ it follows that the left hand side is divisible by $3^3$ and so $3$ divides $n$. It follows that $3$ divides $s$ and we are done.