The Seifert-van Kampen tells us that $\pi_1$ preserves pushouts of the form $U \cap V \subseteq U, V$ (for $U \cap V$, $U$, $V$ open, path-connected).
Can this information be used to say anything about higher homotopy groups, eg. $\pi_2$ using the fact that $\pi_2(X,x)=\pi_1(\Omega X, \mathrm{const}\ x)$?
Ok, so here's a thought.
EDIT: this doesn't work, as $\Omega(U \cup V) \neq \Omega(U) \cup \Omega(V)$
Let $U, V$ open subsets of $U \cup V$. Then $\Omega U$, $\Omega V$ are open in $\Omega (U \cup V)$ in the compact-open topology. To apply Seifert-van Kampen, we need $\pi_0(U) = \pi_0(V) = \pi_0(U \cap V)$ trivial. That is, we require $U$, $V$, $U \cap V$ to be simply connected.
The conclusion being that if $U$, $V$, $U \cup V$ are $n$-connected, and open in $U \cup V$, then $\pi_{n+1}$ preserves the pushout?