Does typesetting of mathematical content differ in right-to-left languages?

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Languages such as Arabic or Hebrew are written right-to-left. Does the way mathematical content is written differ in those languages?

Some simple examples of which I would be interested to know how they are written in righ-to-left languages:

  • $E = mc^2$: Is it eventually written as $c^2 m = E$?
  • Do equations evolve like

\begin{align} ax^2 + bx + c&=0\\ \frac{\pm\sqrt{b^2-4ac} - b}{a \cdot 2} &= x_{1,2}\Leftrightarrow\\ ... &= x_1\Leftrightarrow\\ \end{align}

  • Is the $n$-th root written the same way or is it mirrored?
  • Is $4-1=3$ or $4-1=-3$ or $4-1=3-$?

Are there other differences?