The following $5\times 5$ det. comes from a Russian book. I don't want to expand the det. rather than do some operations on it and extract the result.
Prove:
$$\begin{vmatrix} -1 &1 &1 &1 &x \\ 1& -1 &1 &1 &y \\ 1& 1 & -1 & 1 &z \\ 1& 1 & 1 & -1 & u\\ x& y & z & u &0 \end{vmatrix}= -4 [x^2+y^2+z^2 +u^2 - 2(xy+zx+zu+yz+yu+\color{red}{x}u)]$$
I have tried many things e.g $R_1 \leftrightarrow R_5+ x R_1$ and of course cyclic ($R_2 \leftrightarrow R_5+ y R_2$ etc) and then adding the last row to the second etc. resulting in:
$$\begin{vmatrix} 0 &y+x &z+x &u+x &x^2 \\ y+x&0 &z+y &u+y &y^2 \\ x+z& z+y & 0 &z+u & z^2\\ u+x& u+y &u+z & 0 &u^2 \\ x &y &z &u &0 \end{vmatrix}$$
but does not look that promising.
On the other hand if I add the the first column to the others I do get a lot of zeros, since the first row for example takes the form $-1, 0, 0, 0, x+1$. This looks more promising. But in either case I get stuck.
May I have some hints or answers?
Edit: The red letters as suggested by Peter.
I think this is meant to be an exercise in the use of symmetries, so let's begin by making a few observations.