Let $X \subset \mathbb{R}^n$ be compact and consider the measurable space $(X, \mathcal{B}(X))$ where $\mathcal{B}(X)$ is the Borel $\sigma-$algebra over $X$. Denote by $\mu$ the Lebesgue measure on this space. Let $\nu$ be another measure on this space such that, $\nu \ll \mu$, i.e., it's absolutely continuous w.r.t $\mu$.
Can we always find a measurable mapping $T: X \to X$ such that $T_\# \mu = \nu$, i.e., such the push-forward measure induced by $T$ is equivalent to $\nu$? If not, what conditions one needs to impose on $\nu$ for this to hold?
I am not sure how to approach this, but my intuition is that $T$, if it exists, should be non-singular.
Coincidence of the total measures is an obstruction; morally this should be the only obstruction (in a variety of settings (often when there is more regularity to worry about) this is often named a "Moser Lemma" ($\dagger$)).
Indeed, first let's assume that $X\subseteq \mathbb{R}^n$ is bounded, so that $\text{leb}(X)<\infty$; wlog we may also assume $\text{leb}(X)>0$. Then for any measure $\nu$ on $X$ with $\nu(X)=\text{leb}(X)$, there is a bimeasurable ($\triangle$) $T:X\to X$ such that $T_\ast(\nu)=\text{leb}|_X$ as a corollary of the theorem mentioned in my answer at Is there always a mapping between probability measures on the $n$-sphere?. More generally to apply this theorem all that is required is that $\nu$ assigns zero measure to any point in $X$ ($\star$).
In the case of unbounded $X$ the situation is more subtle. For finite $\nu$ the above argument again applies by one-point compactifying $\mathbb{R}^n$.
More generally if $\nu$ is $\sigma$-finite and if there is a partition $\{X_m\}_m$ of $X$ into countably many pieces with $\nu(X_m)=\text{leb}(X_m)$, or even two partitions $\{X_m\}_m$, $\{X_m'\}_m$with $\nu(X_m')=\text{leb}(X_m)$.
(In an earlier version of this answer I had claimed that $X_m = \{x\in X| m\leq |x|<m+1\}$ would work, which is not correct in general.)
$(\dagger)$ Moser had shown in his paper "On the Volume Elements on a Manifold" the (roughly) following: Let $\omega,\eta$ be two volume elements on a smooth manifold $M$, there is a diffeomorphism $f:M\to M$ with $f^\ast(\omega)=\eta$ iff $\int_M \omega=\int_M \eta$.
Added:
($\triangle$) Thus $T:X\to X$ is a measurable bijection such that $T^{-1}:X\to X$ is also measurable.
($\star$) That is, the condition "for any $x\in X$, $\nu(\{x\})=0$" is sufficient for the argument.