Find the sum of all coefficients in expansion of $(x^2+2x)^{20}$.

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Find the sum of all coefficients in expansion of $(x^2+2x)^{20}$.

Is there a specific method or formula for this?

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The sum of the coefficients of a polynomial is just the value that such polynomial takes in $1$, hence: $$\sum_{n\geq 0}[x^n](x^2+2x)^{20} = (1+2)^{20} = 3^{20}.$$