I have to find this determinant, call it $D$ \begin{vmatrix} \frac12 & \frac1{3}& \frac1{4} & \dots & \frac1{n+1} \\ \frac1{3} & \frac14 & \frac15 & \dots & \frac1{n+2} \\ \vdots & \vdots & \vdots & \ddots & \vdots \\ \frac1{n+1} & \frac1{n+2} & \frac1{n+3} & \dots & \frac1{2n} \end{vmatrix}
As there are no zeros in there, despite being a symmetric matrix, finding this determinant is tough for me. Is there any tricks etc. I do not know any softwares to find this determinant.
I tried to make a pattern by calculating for $n=1,2,3,\dots$
$n=1 \hspace{5cm}D_1=\frac12\\ n=2 \hspace{5cm} D_2=\frac12\frac14-\frac13\frac13\\ \\n=3 \hspace{5cm} D_3=\frac12\frac14\frac16-\frac13\frac13\frac16-\frac12\frac15\frac15-\frac14\frac14\frac14+\frac13\frac14\frac15+\frac13\frac14\frac15$
What I spot from here is, to get $D_2$, (even case)
We get $\frac12\frac14$ by multiplying diagonal entries and then subtracting $\frac1x\frac1x$ where $x=\frac{2+4}2$
Next, to get $D_3$ (odd case), we get our first term i.e. $\frac12\frac14\frac16$ by multiplying diagonal entries and to obtain the rest we follow this pattern that subtract $\frac1x\frac1y\frac1z$, where first we fix $x=2$ and make $y=z=\frac{4+6}2=5$, similarly next we subtract by fixing $x=6$ and $y=z=\frac{2+4}2=3$ and then by fixing $x=4$ and $y=z=\frac{4+4}2=4$, and to get terms that get added we add terms of the form $\frac1x\frac1y\frac1z$ by putting $x=\frac{2+4}2 , y=\frac{4+4}2=4,z= \frac{4+6}2=5$, but we do it $2$ times.
Now out of curiosity I had to calculate $n=4,5$. Here are them-
For $n=4 \text{(even case)} \hspace{3cm} D_4=\frac1{2.4.6.8}-\frac1{2.5.5.8}-\frac1{2.4.7.7}-\frac1{2.6.6.6}\frac1{3.3.6.8}-\frac1{3.4.6.7}-\frac1{5.5.3.7}-\frac1{3.4.6.7}-\frac1{4.4.4.8}-\frac1{4.5.5.6}-\frac1{3.5.5.7}-\frac1{4.5.5.6}-\frac1{4.5.5.6}+\frac1{2.5.6.7}+\frac1{2.5.6.7}+\frac1{4.5.5.6}+\frac1{3.3.7.7}+\frac1{3.4.5.8}+\frac1{3.6.6.5}+\frac1{3.4.5.8}+\frac1{4.4.5.7}+\frac1{4.4.6.6}+\frac1{3.6.6.5}+\frac1{5.5.5.5}+\frac1{4.4.5.7}$.
This helps somewhat in recognizing a pattern in even case, but to be sure one has to find $n=6$ case too.
I guess $n=5$ case will be enough to recognize a pattern, if the one above mentioned in $n=3$ works, as by that, $D_5$ should come out to be
$D_5=\frac1{2.4.6.8.10}- {^5C_2} \text{terms of the form} \frac1{x_1x_2x_3x_4x_5}, \text{where any three terms say} x_1,x_2,x_3$ are fixed out of $2,4,6,8,10$ and $x_4,x_5$ takes values of mean of the other two remaining and similarly for positive terms, but they seem very less number of terms as there were already $12$ negative terms in expansion of $D_4$, so here some more negative terms will appear and their pattern can be known by only finding them, after a few steps, may be upto $n=11$ or $12$, we can see a general pattern appearing.
I am sure after calculating all this that there is a pattern, but may be too complex to find by hand, as calculations gets huge, and it is also probably a hammer to kill an ant, as I am not aware of any other trick, I worked all this out, may be someone can find a quicker solution?
I guess it's easier to go for a reduction formula. I proceed along the generalization mentioned in comment:
Call the determinant $M = M_n(x_1,x_2,\cdots, x_n)$
$$\displaystyle \begin{align}M &= \left|\begin{matrix}\dfrac{1}{x_1+x_1} & \cdots & \dfrac{1}{x_1+x_n}\\ \dfrac{1}{x_2+x_1} & \cdots & \dfrac{1}{x_2+x_n}\\ \cdot & \cdot &\cdot \\ \dfrac{1}{x_n+x_1} & \cdots & \dfrac{1}{x_n+x_n}\end{matrix}\right| \\& \text{subtract R1 from each row} \\&= \left|\begin{matrix}\dfrac{1}{x_1+x_1} & \cdots & \dfrac{1}{x_1+x_n}\\ \dfrac{x_1 - x_2}{(x_2+x_1)(x_1+x_1)} & \cdots & \dfrac{x_1 - x_2}{(x_2+x_n)(x_1+x_n)}\\ \cdot & \cdot &\cdot \\ \dfrac{x_1 - x_n}{(x_n+x_1)(x_1+x_1)} & \cdots & \dfrac{x_1 - x_n}{(x_n+x_n)(x_1+x_n)}\end{matrix}\right| \\&= \prod\limits_{j=2}^{n} (x_1 - x_j)\times \prod\limits_{j=1}^{n}\frac{1}{(x_1+x_j)} \times \left|\begin{matrix}1 & \cdots & 1\\ \dfrac{1}{(x_2+x_1)} & \cdots & \dfrac{1}{(x_2+x_n)}\\ \cdot & \cdot &\cdot \\ \dfrac{1}{(x_n+x_1)} & \cdots & \dfrac{1}{(x_n+x_n)}\end{matrix}\right|\end{align}$$
Again subtracting $\textrm{C1}$ from each column,
$$\begin{align}\left|\begin{matrix}1 & \cdots & 1\\ \dfrac{1}{(x_2+x_1)} & \cdots & \dfrac{1}{(x_2+x_n)}\\ \cdot & \cdot &\cdot \\ \dfrac{1}{(x_n+x_1)} & \cdots & \dfrac{1}{(x_n+x_n)}\end{matrix}\right| &= \left|\begin{matrix}1 & \cdots & 0\\ \dfrac{1}{(x_2+x_1)} & \cdots & \dfrac{x_1 - x_n}{(x_2+x_n)(x_2+x_1)}\\ \cdot & \cdot &\cdot \\ \dfrac{1}{(x_n+x_1)} & \cdots & \dfrac{x_1 - x_n}{(x_n+x_n)(x_n+x_1)}\end{matrix}\right|\\&= \prod\limits_{j=2}^{n} (x_1-x_j) \times \prod\limits_{j=2}^n \frac{1}{x_j+x_1} \times \left|\begin{matrix}1 & \cdots & 0\\ 1 & \cdots & \dfrac{1}{(x_2+x_n)}\\ \cdot & \cdot &\cdot \\ 1 & \cdots & \dfrac{1}{(x_n+x_n)}\end{matrix}\right|\\&= \prod\limits_{j=2}^{n} (x_1-x_j) \times \prod\limits_{j=2}^n \frac{1}{x_j+x_1} \times M_{n-1}(x_2,x_3,\cdots ,x_n)\end{align}$$
Hence, $$M_n(x_1,x_2,\cdots, x_n) = \frac{\prod\limits_{1 \le j < i \le n} (x_i-x_j)^2}{\prod\limits_{1 \le i,j \le n} (x_i+x_j)}$$