Find $v_p\left(\binom{ap}{bp}-\binom{a}{b}\right)$, where $p>a>b>1$ and $p$ odd prime.
Here $v_p(k)$ denotes the largest $\alpha\in\mathbb Z_{\ge 0}$ s.t. $p^\alpha\mid k$.
We have $p\nmid\binom{ap}{bp}$ and $p\nmid \binom{a}{b}$. $$\binom{ap}{bp}-\binom{a}{b}=\frac{(ap)!b!(a-b)!-a!(bp)!(ap-bp)!}{(bp)!(ap-bp)!b!(a-b)!}$$
Let $k=v_2\Big (\tbinom {ap}{bp}-\tbinom{a}{b}\Big)$ :
If we use the well known Lucas's theorem we can easily conclude that $k\geq 1$. In fact, your question was studied by a lot of mathematicians, it's called Ljunggren’s and Jacobsthal’s binomial congruence and some results are:
there are other refinement of this results, a good reference wold be Wolstenholme's theorem