Problem
Given a pre-Hilbert space $\mathcal{H}$.
Consider unbounded operators: $$S,T:\mathcal{H}\to\mathcal{H}$$
Suppose they're formal adjoints: $$\langle S\varphi,\psi\rangle=\langle\varphi,T\psi\rangle$$
Regard the completion $\hat{\mathcal{H}}$.
Here they're partial adjoints: $$S\subseteq T^*\quad T\subseteq S^*$$ In particular, both are closable: $$\hat{S}:=\overline{S}\quad\hat{T}:=\overline{T}$$
But they don't need to be adjoints, or? $$\hat{S}^*=\hat{T}\quad\hat{T}^*=\hat{S}$$ (I highly doubt it but miss a counterexample.)
Application
Given the pre-Fock space $\mathcal{F}_0(\mathcal{h})$.
The ladder operators are pre-defined by: $$a(\eta)\bigotimes_{i=1}^k\sigma_i:=\langle\eta,\sigma_k\rangle\bigotimes_{i=1}^{k-1}\sigma_i\quad a^*(\eta)\bigotimes_{i=1}^k\sigma_i:=\bigotimes_{i=1}^k\sigma_i\otimes\eta$$ and extended via closure: $$\overline{a}(\eta):=\overline{a(\eta)}\quad\overline{a}^*(\eta):=\overline{a^*(\eta)}$$ regarding the full Fock space $\mathcal{F}(\mathcal{h})$.
They are not only formally: $$\langle a(\eta)\varphi,\psi\rangle=\langle\varphi,a^*(\eta)\psi,\rangle$$ but really adjoint to eachother: $$\overline{a}(\eta)^*=\overline{a}^*(\eta)\quad\overline{a}^*(\eta)=\overline{a}(\eta)^*$$ (The usual proof relies on Nelson's theorem, afaik.)
Let $S=\frac{d}{dx}$ and $T=-\frac{d}{dx}$ on the linear subspace $\mathcal{H}=\mathcal{C}_{0}^{\infty}(0,2\pi)\subset \hat{\mathcal{H}}=L^{2}[0,2\pi]$ consisting of infinitely differentiable functions on $[0,2\pi]$ which vanish outside some compact subset of $(0,2\pi)$. Then $$ (Sf,g) = (f,Tg),\;\;\; f,g\in\mathcal{C}_{0}^{\infty}. $$ Both operators $S$ and $T$ are closable in $L^{2}$ and the domains consist of all $f \in L^{2}$ which are absolutely continuous on $[0,2\pi]$ with $f'\in L^{2}$ and $f(0)=f(2\pi)=0$. So $S^{\star} \ne \overline{T}$ and $T^{\star} \ne\overline{S}$ because the domains of the two adjoints are also equal and consist of absolutely continuous $f \in L^{2}$ with $f' \in L^{2}$ (no endpoint conditions.)