Consider $\varphi: U\subset \mathbb{R}^{n-1}\to \mathbb{R}$ a Lipschitz function and $\Omega=Graph(\varphi)$, i.e.,
$$\Omega=\{x=(x_1,...,x_n)\in U\times\mathbb{R};x_n=\varphi(x_1,...,x_{n-1})\}.$$
The set $\Omega$ satisfies the Sphere Condition?
Sphere Condition means that existe $r>0$ (uniform) such that for each $z\in\Omega$, there is $\xi$ satisfying $z\in \partial B_r(\xi)$ and $B_r(\xi)\cap\Omega=\emptyset$.
More generally, if $\Omega$ is only Lipschitz manifold (not necessarily graphic), $\Omega$ satisfies the Sphere Condition?
This is not true. The Lipschitz condition allows for corners, which are bad for the sphere condition. In two dimensions, a simple counterexample is $\varphi(x) = |x_1|-|x_2|$ pictured below.
A sphere containing $(0,0,0)$ has to be either above or below the graph; due to symmetry we may assume it's above it. Then its intersection with the plane $x_2=0$ must be the single point $(0,0,0)$; for otherwise it would be a circle, and a circle cannot stay above the graph of $x_3=|x_1|$. Therefore, the center of the sphere is $(0,r,0)$ where $r$ is its radius. But then the sphere contains the point $(0, r-r/\sqrt{2}, -r/\sqrt{2})$ which is below the graph of $\varphi$.
Here is another example, which works in all dimensions starting with $1$: $\varphi = x_1 \sin \log |x_1|$. This is a Lipschitz function ($\varphi'$ is bounded), but the graph of $\varphi$ meets both $x_n= |x_1|$ and $x_n=-|x_1|$ infinitely often. This rules out a sphere touching the origin from either above or below. The example works in higher dimensions with the same $\varphi$: it just does not depend on $x_2,\dots,x_{n-1}$. The only thing I don't like about this example is that it's impossible to see what goes on from looking at an actual plot of $\varphi$.
But $\varphi = x_1 \sin (10 \log |x_1|)$, which is also Lipschitz, makes a better illustration.