Consider the following claim:
Suppose $G$ and $H$ are groups such that $G \simeq H.$
If $N \triangleleft G$ and $ K \triangleleft H $ are normal subgroups of $G,H$ such that $ N \simeq K $, then $G/N \simeq H/K$.
it seems to me that it should be true, since it looks like a pretty basic property of groups, but $G=H=N=\mathbb{Z}$ and $K=2\mathbb{Z} $ is a counterexample.
Doesn't it show that isomorphism is somewhat a bad tool for researching groups?
You have already found a nice counterexample, so the claim cannot be true. Why is that?
A way to answer this could be by saying that: $G\cong H$ is not enough, we need to know what the isomorphism is.
If you have a specific isomorphism $f:G\to H$, then any normal subgroup $N$ of $G$ is sent via $f$ to a normal subgroup $K$ of $G$, and then we do have $G/N\cong H/K$. Without knowing this relationship between $H$ and $K$, nothing much can be said.
So an idea to keep in mind would be that existence of an isomorphism between two groups is good, but a specific isomorphism is better.
Nevertheless, isomorphisms are still a good tool to study groups, since many properties (abelian-ness, solvability, representation theory, etc.) only depend on the isomorphism class of a group.