How are analytic continuations computed?

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Suppose I define some analytic function on some domain $\Omega_1$ and I want to extend this function to the unique analytic continuation on $\Omega_2$. Are there any general methods of computing the unique analytic continuation? Is the analytic continuation more nuanced than say replacing the $x$ with a $z$ if $\Omega_1 = \mathbb{R}$?