How does one usually evaluate the expected value of observed Fisher information?

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How does one usually evaluate the expected value of observed Fisher information?

That is what does

$$\mathcal{I}(\theta)=-E\left[\frac{\partial^2}{\partial\theta^2}l(X,\theta)\mid\theta\right]$$

evaluate to?

Particularly, how is $E$ treated? How does $E$ apply to the derivatives?