How to define Chirality and Polarity on a graph?

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Is there a concept of Chirality or Polarity defined on graphs?

For example, consider a system with spin-$1/2$ (up/down polarity) particles which have also chirality (right/left).

I thought to take a simple graph representation of Ising model and somehow extend it.

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I would say that a graph/percolation model for liquid-crystal is what I am looking for at the end.

I guess a 4-coloring approach should work here. I am not sure how to state it for doing physics purposes.