Now I think this is true:
Let $A$, $B$, $C$ and $D$ be symmetric, positive definite matrices and suppose that $E:=ABCD $ is symmetric. How might I prove that $E$ is also positive definite?
the similar question can see: How to prove that $D := ABC$ is also positive definite?
@Landscape this not true, Really? Thank you everyone
You cannot prove it, because there is a counterexample. Let
$$A = \begin{bmatrix} 58 & 50 & 30 \\ 50 & 66 & 38 \\ 30 & 38 & 22 \end{bmatrix}, \quad B = \begin{bmatrix} 8 & 6 & 8 \\ 6 & 5 & 4 \\ 8 & 4 & 65 \end{bmatrix}, \quad C = \begin{bmatrix} 34 & 26 & 46 \\ 26 & 56 & 52 \\ 46 & 52 & 83 \end{bmatrix}, \quad D = \begin{bmatrix} \frac{176398144863}{734764024} & \frac{2084349747}{734764024} & -\frac{401393975}{91845503} \\ \frac{2084349747}{734764024} & 123 & 74 \\ -\frac{401393975}{91845503} & 74 & 45 \end{bmatrix}.$$
Then $$ABCD = \begin{bmatrix} \frac{3747748968739763}{91845503} & \frac{4372037328164921}{91845503} & \frac{2546983749851550}{91845503} \\ \frac{4372037328164921}{91845503} & \frac{5099682487522571}{91845503} & \frac{2970895299665430}{91845503} \\ \frac{2546983749851550}{91845503} & \frac{2970895299665430}{91845503} & \frac{1730738016057502}{91845503} \end{bmatrix}.$$
$A$, $B$, $C$, $D$ are symmetric positive definite, while $ABCD$ is symmetric, but not positive semidefinite (the determinant of the principal leading submatrix of order $2$ is $-2.82211 \cdot 10^{11}$).
This was generated by few runs of the Mathematica code:
The line
Map[MatrixForm, all]outputs all five (the above are a minor edit of such output withTeXForminstead ofMatrixForm), while the last line checks their positive definitess, with the outputIn case you want to test these matrices for yourself, here is the Mathematica output for them:
Hopefully, I didn't mess up these while editing. Just in case, I'll keep Mathematica running with the above solution for few more hours, in case you have some questions.