How can we reduce this differential equation into first-order differential equation?
$\left( {\frac {\rm d}{{\rm d}z}}U \left( z \right) \right) ^{3}{ \frac {{\rm d}^{2}}{{\rm d}{z}^{2}}}U \left( z \right) + \left( { \frac {\rm d}{{\rm d}z}}U \left( z \right) \right) {\frac {{\rm d}^{4 }}{{\rm d}{z}^{4}}}U \left( z \right) - \left( {\frac {{\rm d}^{2}}{ {\rm d}{z}^{2}}}U \left( z \right) \right) {\frac {{\rm d}^{3}}{ {\rm d}{z}^{3}}}U \left( z \right) =0 $
Set $V=U'$, then $$ V^3V'+VV'''-V'V''=0. $$ The last two terms look like the numerator of a quotient derivative $$ VV'+\left(\frac{V''}{V}\right)'=0 $$ Set $W=\frac12V^2+\frac{V''}{V}$, then $W'=0$ and $$ V''+\frac12V^3=VW $$ So if the components of the state vector are $X=[U,V,V',W]^T$, then $$ X'=[V,V', VW-\frac12V^3,0]^T, $$ that is $$ X'=\pmatrix{X_1'\\X_2'\\X_3'\\X_4'} =F(x)=\pmatrix{X_2\\X_3\\X_2X_4-X_2^3/2\\0} $$ Compared to the simpler first order system using the derivatives vector to $U$, this requires a non-trivial transformation of the initial value for $W(z_0)$. The advantage here is that the right side has no divisions by variable expressions. One could also eliminate $W$ as component and just use it as constant (depending on the initial value), thus reducing the dimension of the system.