Let $N\triangleleft{A}$ and ${A}/{N}\cong{B}$ for some non-trivial groups $A$ and $B$. Then, is the expression $N\cong{A}/{B}$ valid in general? If not, are there any conditions for its validity?
In particular, I have in hand the expressions:
$${{\pi }_{1}}{{\left( H \right)}_{G}}\triangleleft {{\pi }_{1}}\left( H \right)\quad\text{and}\quad{{{\pi }_{1}}\left( H \right)}/{{{\pi }_{1}}{{\left( H \right)}_{G}}}\;\overset{\mathbf{Grp}}{\mathop{\cong }}\,{{\pi }_{1}}\left( G \right)$$
where $H\le G$ is a topologically closed subgroup of the Lie group $G$ and ${{\pi }_{1}}{{\left( H \right)}_{G}}$ is the set of homotopy groups of loops that are trivial when embedded in $G$, i.e. the kernel of $i_*$, where $i\colon{H}\to{G}$ is the inclusion map. I would like from these to infer that: $${{\pi }_{1}}{{\left( H \right)}_{G}}\overset{\mathbf{Grp}}{\mathop{\cong }}\,{{{\pi }_{1}}\left( H \right)}/{{{\pi }_{1}}\left( G \right)}$$ whithout any assumptions on the connectedness of the relevant groups, except from: $${{\pi }_{0}}\left( H \right)\overset{\mathbf{Set}}{\mathop{\cong }}\,{{\pi }_{0}}\left( G \right)$$ If these conditions are not enough to get to the desired result, what other assumptions shall I include?
So, for general groups the first part of the answer is negative. What about the part involving the homotopy groups? Is there any loophole there? Even if I have to relax the conditions on connectedness of $G$ and $H$ and assume that one of them (therefore the other, also) is path-connected? This would imply, if I am correct, that the fundamental groups Abelianize.
To answer your general question from your first paragraph: no, it's not valid. And the reason is that $B$ may not be a subgroup of $A$ at all, so the expression "$A/B$" wouldn't even make sense. Here's a quick example: $A=\mathbb{Z}$ and $N=2\mathbb{Z}$. Then $A/N=\mathbb{Z}/2\mathbb{Z}=\mathbb{Z}_2$, and there's no such subgroup in $A$.