It has come to my attention that the cross products of the vectors $\mathbf{i}$, $\mathbf{j}$, and $\mathbf{k}$ are almost identical to the products of the imaginary components of quaternions $i$, $j$, and $k$. If one were to ignore the real portion of quaternions, could one find cross products by representing the vectors as quaternions?
Another question: would it be possible to use quaternions to find cross products of Cartesian vectors in $(x, y, z, t)$? If so, could this be used as a representation of physical entities such as space-time?
No, this is not possible. There is a superficial simmilarity but there is also a big difference: while ${\bf i} \times {\bf i} = 0$, $i \cdot i = -1$. In other words, imaginary quaternions are not closed under multiplication and thus don't form an algebraic structure.
Nevertheless, there is a relation to vector products, albeit a little bit deeper. The unit quaternions $a + ib + jc + kd$ such that $a^2 + b^2 + c^2 + d^2 = 0$ with multiplication are isomorphic to a Lie group knows as $SU(2)$. This group has as a Lie algebra the algebra of traceless skew-hermitian matrices ${\frak su}(2)$ with operation that of commutator which as a matter of fact is isomorphic to $\mathbb R^3$ with vector product as its operation.
Regarding the other question of $(x,y,z,t)$, the answer is again no. The vector product structure is only available in three-dimensions and that's because fundamentally it comes from a commutator operation on skew-symmetric matrices (this gives isomorphism with another Lie algebra, this time ${\frak so}(3)$) and the dimension of this algebra coincides with the dimension of the space only for $d=3$.