Fix a topological space $X$, and fix abelian sheaves $\mathscr{F}$ and $\mathscr{G}$ on $X$, and recall the definition of sheaf Hom, $\operatorname{\mathscr{H}\!\mathit{om}}_{\mathscr{O}_X}(\mathscr{F},\mathscr{G})$. Here, I am using $\operatorname{Hom}_{\mathscr{O}_{X,x}}(\mathscr{F}_x,\mathscr{G}_x)$ simply to refer to the Hom in the category of $\mathscr{O}_{X,x}$-modules. Note that we have a canonical map $$\operatorname{\mathscr{H}\!\mathit{om}}_{\mathscr{O}_X}(\mathscr{F},\mathscr{G})\to\operatorname{Hom}_{\mathscr{O}_{X,x}}(\mathscr{F}_x,\mathscr{G}_x)$$ sending $\langle U,\varphi\rangle\in \operatorname{\mathscr{H}\!\mathit{om}}_{\mathscr{O}_X}(\mathscr{F},\mathscr{G})$ to $\varphi_x\in\operatorname{Hom}_{\mathscr{O}_{X,x}}(\mathscr{F}_x,\mathscr{G}_x)$. I suspect that this map is not an isomorphism, but I can't prove it.
2026-03-31 20:37:45.1774989465
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Is $\mathscr{H\!}\mathit{om}_{\mathscr{O}_X}(\mathscr{F},\mathscr{G})_x\cong\operatorname{Hom}_{\mathscr{O}_{X,x}}(\mathscr{F}_x,\mathscr{G}_x)$?
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For schemes, this is just a special case of Does localisation commute with Hom for finitely-generated modules? (recall how modules correspond to quasi-coherent sheaves). In general the answer is no, but yes for coherent sheaves (more generally, finitely presented sheaves).
This is not an isomorphism in general. Here is an example in the category of sheaves (so with $\mathcal{O}_X=\mathbb{Z}$).
Let $\mathcal{F}=i_*\mathbb{Z}$ where $i:\{0\}\rightarrow\mathbb{R}^n$ is the inclusion of the origin. Let $\mathcal{G}=\mathbb{Z}$. I claim that $\mathcal{H}om(i_*\mathbb{Z},\mathbb{Z})=0$. Indeed, obviously $\operatorname{Hom}(i_*\mathbb{Z}_{|U},\mathbb{Z}_{|U})=0$ for all $U\not\ni 0$, and in the case where $0\in U$, we can assume that $U$ is an open ball, and we can assume that this ball is $\mathbb{R}^n$ (by homeomorphism). So we are reduced to prove that $\operatorname{Hom}(i_*\mathbb{Z},\mathbb{Z})=0$. Let $j:\mathbb{R}^n\setminus\{0\}\rightarrow\mathbb{R}^n$ be the inclusion of the complement. By the short exact sequence $$0\rightarrow j_!\mathbb{Z}\rightarrow\mathbb{Z}\rightarrow i_*\mathbb{Z}\rightarrow 0$$ we see that $\operatorname{Hom}(i_*\mathbb{Z},\mathbb{Z})$ is the kernel of $\operatorname{Hom}(\mathbb{Z},\mathbb{Z})\rightarrow\operatorname{Hom}(j_!\mathbb{Z},\mathbb{Z})$. But this map is injective (even an isomorphism if $n\geq 2$), because $\operatorname{Hom}(j_!\mathbb{Z},\mathbb{Z})=\operatorname{Hom}(\mathbb{Z},j^{-1}\mathbb{Z})=\mathbb{Z}^{\pi_0(\mathbb{R}^n\setminus\{0\})}$.
This prove that $\mathcal{H}om(i_*\mathbb{Z},\mathbb{Z})=0$ and so are its stalks. However, $\operatorname{Hom}((i_*\mathbb{Z})_x,\mathbb{Z}_x)=\operatorname{Hom}(\mathbb{Z},\mathbb{Z})=\mathbb{Z}$.