Let $M$ and $N$ be real manifolds of dimension $n$ which happen to admit complex structures (so that necessarily $n=2k$ and both are orientable). Then does their connected sum $M\# N$ also admit a complex structure?
This is true for $n=2$, because every oriented $2$-dimensional topological manifold admits a complex structure. However, this operation doesn't seem to be compatible with the information given by the structure; in particular we would want $M\sqcup N$ to at least be almost-complex cobordant to $M\# N$, or that these two manifolds should have the same Chern numbers. We have $$c_1[M\sqcup N]=\langle c_1(\tau M\sqcup\tau N),[M\sqcup N]\rangle = \langle c_1(\tau M),[M]\rangle + \langle c_1(\tau N),[N]\rangle = c_1[M]+c_1[N] $$ But then recall that the first Chern class of a complex rank 1 bundle $V$ is the Euler class of its realification, and so the first Chern number of a complex 1-manifold is its Euler characteristic. Thus $$c_1[M\# N] = \chi(M\#N)=\chi(M)+\chi(N)-2 \neq c_1[M] + c_1[N] $$ So it seems like it's possible that the fact that complex $1$-manifolds are closed under connected sum could be a coincidence.
In higher dimensions there are no complex structures on $S^{2k}$ (except MAYBE $S^6$). But, in the positive direction, there ARE these complex Calabi-Echkmann manifolds homeomorphic to $S^{2k+1}\times S^{2l+1}$. So does anyone know if, for example, the connected sum of $g$ copies of $S^5\times S^5$ admits a complex structure for any $g>1$?
EDIT: I am greatly appreciative of Aleksandar Milivojevic for pointing out the first paragraph of my original answer is false, and therefore does not give a proof of the following two paragraphs. (For instance, $K3 \# \overline{K3}$ supports no complex structure: Aleksandar kindly explained to me that this has signature zero but Euler characteristic $46$, and $\chi + \sigma$ is always divisible by $4$ on an almost complex 4-manifold.
I leave these here for posterity, separated from the correct content by lines. It remains an interesting question whether or not $M \# N$ can support a complex structure when $M$ and $N$ are singly-even dimensional complex manifolds. There is no obstruction coming from the nonexistence of an almost complex structure, so it is not totally impossible.
Let $M$ and $N$ be complex manifolds. Because we have a local form (there is a neighborhood of a point isomorphic to the the complex unit disc) you can verify that $M \# \overline N$ has a natural complex structure - just line up the copies of $\Bbb C^n \setminus \{0\}$ you're gluing together so the almost complex structures match up. Then the Nijenhuis tensor still vanishes.
So, if $N$ supports a complex structure, does $\overline N$? This would mean that $M \# N$ supports a complex structure. If $\text{dim}(N) = 4n+2$, then this is true: if $J$ is your (integrable almost) complex structure, then the complex conjugate $\overline J$ gives a complex structure on $\overline N$. The reason this doesn't work in dimension $4n$ is because $\overline J$ induces the same orientation as $J$!
So I wouldn't quite call it a fluke. It's true for every $4n+2$-dimensional complex manifold, not just $2$-dimensional ones. But it's not true in every dimension.
For 4-manifolds, it is a theorem of Wu that $M$ admits an almost complex structure with $c_1(J) = c \in H^2(M;\Bbb Z)$ if and only if $c$ reduces to $w_2$ mod 2, and $c^2 = 3\sigma + 2\chi$. You can prove using this criterion that a most two of $M, N$, and $M \# N$ can admit almost complex structures; in particular, $\Bbb{CP}^2 \# \Bbb{CP}^2$ cannot admit an almost complex structure.
I don't know about higher dimensions $4n$. It might be wise to think about almost complex structures instead of complex ones first, because those are easier to work with and there are no known high dimensional (complex dimension $> 2$) examples of almost complex manifolds that do not admit a complex structure.