$\left( \begin{array}{ccc} 1 & 1000 & 2 & 3 &4\\ 5 & 6 &7&1000 &8\\ 1000&9&8&7&6\\ 5 & 4&3&2&1000\\ 1&2&1000&3&4\\ \end{array} \right)$
When I compute the determinant online, I find that it is positive, but I'm supposed to "see" something about the matrix that allows me to know the determinant is positive. What properties does this specific matrix have that allow you to deduce the determinant will be positive?
With an even number of adjacent row swaps, you can put the $1000$s on the diagonal. That determinant must be positive. Using the algorithm which looks at minors, the largest term is always positive.