Let $n \in \{ 1, 2, 3, \ldots \}$ be fixed and set $N = \{ 1, \ldots, n \}$. Let $X_1, \ldots, X_n$ be measure spaces and for $I = \{ i_1, \ldots, i_m \} \subseteq N$ set $X^I = X_{i_1} \times \cdots \times X_{i_m}$ and let $\int f \, dx^I$ denote the integral $\int \cdots \int f(x_1, \ldots, x_n) \, dx_{i_1} \, \cdots \, dx_{i_m}.$
Then, if $J \subseteq I$ we have a linear map $\operatorname{res}_{I \to J} : L^1(X^I) \to L^1(X^J)$ defined by $f \mapsto \int f \, dx^{I \setminus J}.$ This map works as restriction morphisms for a presheaf.
Question: Can this presheaf be generalized in some natural way to cases where $N$ is not a discrete space but continuous like $\mathbb{R}^d$?
I'm not sure why one would want to mess with $N$. It seems to me that there is a natural sheaf of $L^p$ functions on a (Borel) measure space $X$, in the way that you have defined. Indeed, this is a pre-sheaf and in fact it is flabby. In the special case that $X$ is a product of measure spaces, then there is a natural restriction map to the inclusion of any of its summands.