Problem. Let $a_1/b_1,\ldots,a_n/b_n$ be rational numbers in lowest terms. If $M={\rm lcm}(b_1,\ldots,b_n)$, prove that the gcd of $Ma_1/b_1,\ldots,Ma_n/b_n$ is $1$.
I think this statement is false. For example, consider $$\frac{2}{3}\quad{\rm and}\quad \frac{2}{9}.$$ Both of them are in the lowest form, but $M={\rm lcm}(3,9)=9$ where $$9\cdot\frac{2}{3}=6\quad{\rm and}\quad 9\cdot\frac{2}{9}=2$$ are not relatively prime.
Nonetheless, if I add the assumption that $\gcd(a_1,\ldots,a_n)=1$, will the assertion be true? I tried writing $1$ as a linear combination of those numbers, but it seems not working.
With your added assumption
$$\gcd(a_1, \, \ldots \, , a_n) = 1 \tag{1}\label{eq1A}$$
then the statement of
$$\gcd\left(\frac{Ma_1}{b_1}, \, \ldots \, , \frac{Ma_n}{b_n}\right) = d \tag{2}\label{eq2A}$$
having $d = 1$ is true. To prove this, assume instead that $d \gt 1$ so there's a prime $p \mid d$. There are $2$ basic cases to consider.
First, there's at least one $1 \le i \le n$ where $p \mid \frac{M}{b_i}$. This means there's one or more $1 \le j \le n$ where $p \mid b_j$, so there's also one or more indices where the exponent of $p$ in the prime factorization of $b_j$ is a maximum, call it $m$. Choose any one of these indices, call it $k$. The definition of $\operatorname{lcm}$ means that $M$'s exponent of $p$ in its prime factorization is also the maximum among all of the $b_i$, so it's the same as that of $b_k$, i.e., it's $m$ for both, meaning that $p \not\mid \frac{M}{b_k}$. As such, due to $d$ being the $\gcd$ in \eqref{eq2A}, this requires that $p \mid a_k$ instead. However, since $p \mid b_k$, this means $\frac{a_k}{b_k}$ is not in lowest terms, which is not allowed.
Thus, the second case must apply, i.e., there are no $i$ where $p \mid \frac{M}{b_i}$. This means $p \mid a_i$ for all $1 \le i \le n$ instead. However, this contradicts your added assumption in \eqref{eq1A}.
These contradictions in the $2$ possible cases mean the original assumption of $d \gt 1$ must be false, i.e., it must be that $d = 1$ in \eqref{eq2A} instead.