Question: Other than the zero map, what linear map has the same matrix $A_{E,F}$ with respect to all $E$ and $F$?
For linear map $T:\mathbb{R}^n \rightarrow \mathbb{R}^n$, given a basis $E$ for domain and basis $F$ for codomain, I can find a unique corresponding matrix $A_{E,F}$, where $A_{E,F}$ generally depends on $E$ and $F$.
Note that for any $E$ and $F$, the matrix corresponding to the zero map is always the zero matrix, since the map sends all vectors in $E$ to $\mathbf{0}$, and $\mathbf{0}$ can only be represented by $(0,...,0)$ with respect to any basis $F$.
If $T \ne 0$, then there exists $v \in \mathbb R^n \setminus \{0\}$ such that $w = T(v) \ne 0$. There exists a basis $E =\{e_1,\ldots,e_n\}$ of $\mathbb R^n$ such that $e_1 = v$ and a basis $F =\{f_1,\ldots,f_n\}$ of $\mathbb R^n$ such that $f_1 = w$.
Write $A_{EF} = (a_{ij})$. Then $f_1 = w = T(v) = T(e_1) = \sum_{j=1}^n a_{1j}f_j$ which implies $a_{11} = 1$ and $a_{1j} = 0$ for $ j > 1$.
Now take the basis $F' = \{f'_1,\ldots,f'_n\}$ of $\mathbb R^n$ with $f'_j = \frac 1 2 f_j$ and write $A_{EF'} = (a'_{ij})$. Then $2f'_1 = w = T(v) = T(e_1) = \sum_{j=1}^n a'_{1j}f'_j$ which implies $a'_{11} = 2$ and $a'_{1j} = 0$ for $ j > 1$.
Thus $A_{EF} \ne A_{EF'}$.