$(E) :\qquad x^2y'=y^2e^{\frac{x}{y}}+xy$
Attempt :
Let $z:=\dfrac{y}{x}$ thus $z'=\dfrac{xy'-y}{x^2}\iff x^2z'=xy'-y\iff y'=xz'+\dfrac{y}{x}\iff y'=xz'+z$
We deduce that $x^2(xz'+z)=(xz)^2e^{1/z}+x^2z\iff x^3z'=x^2z^2e^{1/z}\iff xz'=z^2e^{1/z}$
So $\displaystyle \dfrac{z'}{z^2e^{1/z}}=\dfrac{1}{x}\iff \int \dfrac{1}{s^2e^{1/s}}\cdot ds=\int\dfrac{1}{x}\cdot dx$, can we go further?
Observe that $$ \frac{\rm d}{{\rm d}x}e^{-x/y}=e^{-x/y}\frac{xy'-y}{y^2}. $$ The original equation is equivalent to $$ x\frac{xy'-y}{y^2}=e^{x/y}\iff\frac{\rm d}{{\rm d}x}e^{-x/y}=\frac{1}{x}, $$ So straightforwardly, $$ y=-\frac{x}{\log\left(\log x+C\right)} $$ for some constant $C$.
Here $x$ and $y$ are supposed to be real.