Non Separable ODE

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I have a function in the following form.

$$P = \frac{K_1}{2} U\left[\sqrt{\frac{2K_1}{K_2 U^2} + 1} +1\right]$$

where $P =\dfrac{dE}{dt}$ and $U =\dfrac{dS}{dt}$

I want to find energy $E$ required to travel distance $S$.
If I integrate both sides with respect to $dt$ I think i will get what I want. but how to do it ?

Can anyone point this out to me ?

Thanks

PS : This is not a homework problem. I'm just a curious old man who is not good at maths.