I need some help with this question:
If a license plate for a vehicle consist of five characters: $4$ digits (the first of which cannot be $0$), followed by one letter of the alphabet (which cannot be $I$ or $O$), how many different license plates are possible?
The first condition means that you have to choose from the $9000$ numbers between $1000$ and $9999$. The second one, assuming that your alphabet contains $25$ characters, means that you the letter can be any of $23$ different ones. With no further restriction, the number of combinations is $$9000 \cdot 23.$$ If you prefer, the first part you could also view as 4 separate digits, so that there are 9 combinations for the first one, and 10 for the remaining three, which nets you $$9 \cdot 10 \cdot 10 \cdot 10 \cdot 23$$ total combinations.
Edit: Okay, after seeing the other answers and counting thrice, I now see how to arrive at $26$ letters instead of $25$ ...