If the calculation of the triple integral is required:
$$ I = \iiint\limits_A f(x,\,y,\,z)\,\text{d}x\,\text{d}y\,\text{d}z\,, \quad \text{with} \; f(x,\,y,\,z) = x^1+y^3+z^5\,, \quad A = \{x^2+y^4+z^6 \le 1\} $$
I would notice that:
domain $A$ enjoys the symmetry $S(x,\,y,\,z) = (-x,\,-y,\,-z)$, i.e. $S(A) = A$;
the function $f$ is odd with respect to $S$, i.e. $S(f)=-f$;
therefore, without any calculation, I can conclude that $I=0$.
On the other hand, if you were to calculate the double integral:
$$ J = \iint\limits_B g(x,\,y)\,\text{d}x\,\text{d}y\,, \quad \text{with} \; g(x,\,y) = \frac{x\,y}{x^2+y^2}\,, \quad B = \{1 \le x^2+y^2 \le 4,\,y \ge x\} $$
through a transformation of coordinates from Cartesian to polar in the plane it is easy to prove that $J = 0$, but I cannot find a way to prove it as above, that is by identifying a symmetry $S$ for $B$ in which $g$ is odd. Ideas?

Let $C:=\{(x,y)\in B:x+y\geqslant 0\}$, and $f(x,y):=(-y,x)$.
Then $B=C\cup f(C)$, $C\cap f(C)$ is a nullset, and $g\circ f=-g$.