Partial derivatives with respect to $x$, $y$ and $z$.
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If you calculate $\dfrac{\partial F}{\partial x}$, that means you hold $y$ and $z$ fixed. So: $\dfrac{\partial F}{\partial x} = \dfrac{-cos(y^2 - x)}{z + sin(y^2 - x)}$
$\dfrac{\partial F}{\partial y} = \dfrac{2y \cdot cos(y^2 - x)}{z + sin(y^2 - x)}$
$\dfrac{\partial F}{\partial z} = \dfrac{1}{z + sin(y^2 - x)}$
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If you calculate $\dfrac{\partial F}{\partial x}$, that means you hold $y$ and $z$ fixed. So: $\dfrac{\partial F}{\partial x} = \dfrac{-cos(y^2 - x)}{z + sin(y^2 - x)}$
$\dfrac{\partial F}{\partial y} = \dfrac{2y \cdot cos(y^2 - x)}{z + sin(y^2 - x)}$
$\dfrac{\partial F}{\partial z} = \dfrac{1}{z + sin(y^2 - x)}$