I can use the fact that $\log(n) \in O(n)$ and $n \notin O(\log(n))$.
So assume for the sake of contradiction that $n^2 \in \Omega(2^n)$.
Hence, there exists some $c > 0$ and $k > 0$ such that for all $n > k$ we have $c \cdot 2^n \leq n^2$.
Hence, we have that $\log(c) + 2\log(n) \leq n\log(2)$. Hence, $\log(c) \leq n\log(2) - 2\log(n)$.
I know that $n\log(2) - 2\log(n)$ approaches negative infinity. But I'm having trouble showing this formally using $\log(n) \in O(n)$ but $n \notin O(\log(n))$. And I can't use any other facts from calculus.
Hint: You know that $$\lim_{n \to \infty} \frac{\log_2 n}{n} = 0.$$ This means that means that for any positive constant $k$, $k \log_2 n - n$ gets arbitrarily large and negative as $n$ increases (why?). What does this imply about the quantity $2^{2 \log_2 n - n}$?