Suppose $A$ is a matrix. The $(i, j)$-entry of $A$ is denoted as $[A]_{i,j}$.
Suppose that $a_1$, $a_2$, $\dots$, $a_n$ are $m \times 1$ matrices. Then $[a_1, a_2, \dots, a_n]$ is the $m \times n$ matrix whose $(i, j)$-entry is equal to $[a_j]_{i,1}$. The piece of notation allows one to display a matrix using its columns.
Determinants are defined here.
How does one prove the antisymmetric property?
Suppose that $q$ is a positive integer less than or equal to $n$. Suppose that $p$ is a positive integer less than $q$. Suppose that $a_1$, $a_2$, $\dots$, $a_n$ are $n \times 1$ matrices. Then $$ \det {[a_1, \dots, \overset{\text{column}\,p}{a_q}, \dots, \overset{\text{column}\,q}{a_p}, \dots, a_n]} = -\det {[\dots, a_p, \dots, a_q, \dots]}. $$
Let the proposition $P(n)$ be as follows:
For any $n \times 1$ matrices $a_1$, $a_2$, $\dots$, $a_n$, any positive integer $q$ less than or equal to $n$, any positive integer $p$ less than $q$, $$ \det {[a_1, \dots, \overset{\text{column}\,p}{a_q}, \dots, \overset{\text{column}\,q}{a_p}, \dots, a_n]} = -\det {[\dots, a_p, \dots, a_q, \dots]}. $$
It is easy to check that $P(2)$ is true: $$ \det {\begin{bmatrix} a & c \\ b & d \\ \end{bmatrix}} = ad - bc = -(cb - da) = -\det {\begin{bmatrix} c & a \\ d & b \\ \end{bmatrix}}. $$
Suppose that $P(n-1)$ is true (in which $n \geq 3$). I need to show that $P(n)$ is true.
I know that it suffices to prove that swapping two adjacent columns changes the sign. Suppose that one has proved it. Suppose that $p < q$. It can be shown that swapping columns $p$ and $q$ amounts to swapping two adjacent columns $2(q - p) - 1$ times, which ultimately changes the sign: $$ \begin{aligned} 0\colon & \dots, p, p+1, p+2, \dots, q-1, q, \dots \\ 1\colon & \dots, p+1, p, p+2, \dots, q-1, q, \dots \\ {} & \vdots \\ q-p\colon & \dots, p+1, p+2, \dots, q-1, q, p, \dots \\ q-p+1\colon & \dots, p+1, p+2, \dots, q, q-1, p, \dots \\ {} & \vdots \\ q-p+(q-p+1)\colon & \dots, q, p+1, p+2, \dots, q-1, p, \dots \\ \end{aligned} $$
However, I do not know how to prove the special case.
This proof is direct, which is based on the fact that the determinant of a square matrix can be computed by expansion about any column.
I will prove that $P(n)$ (in the description of the question) is true for $n = 2$, $3$, $\dots$ by mathematical induction.
It is easy to check that $P(2)$ is true.
Suppose that $P(n-1)$ is true (in which $n \geq 3$). I will prove that $P(n)$ is true under the hypothesis.
Choose a positive integer $q$ less than or equal to $n$. Choose a positive integer $q$ less than $p$. Define $$ \begin{aligned} & A = [\dots, a_p, \dots, a_q, \dots], \\ & B = [\dots, a_q, \dots, a_p, \dots], \end{aligned} $$ in which $B$ is obtained from $A$ by interchanging the location of columns $p$ and $q$.
Choose a positive integer $u$ less than or equal to $n$ so that $u \neq p$ and that $u \neq q$. Note that $B(i|u)$ can be seen as the matrix obtained from $A(i|u)$ by interchanging the location of two columns (for $i = 1$, $2$, $\dots$, $n$). By the hypothesis, $\det {(B(i|u))} = -\det {(A(i|u))}$. Note that $[B]_{i,u} = [A]_{i,u}$. Hence $$ \begin{aligned} \det {(B)} = {} & \sum_{i = 1}^{n} {(-1)^{i+u} [B]_{i,u} \det {(B(i|u))}} \\ = {} & \sum_{i = 1}^{n} {(-1)^{i+u} [A]_{i,u} (-\det {(A(i|u))})} \\ = {} & {-\sum_{i = 1}^{n} {(-1)^{i+u} [A]_{i,u} \det {(A(i|u))}}} \\ = {} & {-\det {(A)}}. \end{aligned} $$
Hence by mathematical induction, $P(n)$ is true for $n = 2$, $3$, $\dots$.
Note that the proof works with any two columns, which are not necessarily adjacent.